What is larval therapy?

Larval therapy, also known as <a href="https://www.wikiwhat.page/kavramlar/Maggot%20Debridement%20Therapy">Maggot Debridement Therapy</a> (MDT), is a type of biotherapy involving the introduction of live, disinfected fly larvae (maggots) into non-healing wounds of a human or animal for the purpose of cleaning dead tissue and promoting healing.

Here's a breakdown:

• How it works: The maggots selectively ingest necrotic (dead) tissue, thereby cleaning the wound. They also secrete enzymes that help break down dead tissue and stimulate the formation of new tissue. Their activity can also help to disinfect the wound.

• Types of maggots: Sterile, laboratory-reared larvae of the green bottle fly (Lucilia sericata) are typically used. These are raised under strictly controlled conditions to prevent infection.

• Indications: MDT is often used for chronic wounds that are not responding to conventional treatments, such as:

  • <a href="https://www.wikiwhat.page/kavramlar/Diabetic%20Foot%20Ulcers">Diabetic Foot Ulcers</a>
  • <a href="https://www.wikiwhat.page/kavramlar/Pressure%20Sores">Pressure Sores</a> (bedsores)
  • <a href="https://www.wikiwhat.page/kavramlar/Venous%20Leg%20Ulcers">Venous Leg Ulcers</a>
  • Surgical wounds

• Benefits:

  • Effective debridement (removal of dead tissue)
  • Reduced bacterial load in the wound
  • Stimulation of wound healing
  • Can reduce the need for amputation in some cases.

• Procedure: A healthcare professional places the maggots into the wound and covers them with a sterile dressing. The maggots remain in the wound for a specified period (usually 1-3 days) before being removed. The process may be repeated as needed.

• Risks and Side Effects: While generally safe, some potential side effects include:

  • Pain or discomfort
  • Tickling or crawling sensation
  • Itching
  • Anxiety or psychological distress

• Contraindications: MDT may not be suitable for all patients. Contraindications include:

  • Wounds with significant arterial insufficiency
  • Severe bleeding disorders
  • Allergy to fly larvae

• History: The use of maggots for wound healing dates back centuries. Modern MDT was re-introduced in the 1990s.

• Regulation: MDT is regulated in many countries as a medical device.